Cell Culture Applications

Introduction
Cell culture and brain slice applications involve recording from either multi-electrode array (MEA) plates or from individual microelectrodes inserted into the preparation from above. Recordings from MEA plates typically involve testing the effects of drugs or toxins, and can extend over many days or even weeks. MEA plates can be obtained from a variety of vendors, including the University of North Texas, Multichannel Systems, and Panasonic Alpha-MED Sciences.

The following types of signals are typically acquired and analyzed in cell culture and brain slice experiments:

• Action potentials and local field potentials from MEA electrode plates
• Timing of external stimuli (for example, light onset/offset, electrical stimulation, among others)
• Trial-based and time-based recording

Relevant Plexon products for cell culture and brain slice experiments:

• MEA Workstation
• Offline Sorter
• Neuroexplorer

Sample papers from Plexon customers recording from cell cultures and brain slices

Related third-party products:

• University of North Texas MEA plates
• Multichannel systems MEA plates
• Panasonic Alpha-Med MEA plate